Medical uses Levamisole

1 medical uses

1.1 worms
1.2 cancer
1.3 other

medical uses
worms

levamisole used anthelmintic treat worm infestations in both humans , animals. levamisole works nicotinic acetylcholine receptor agonist causes continued stimulation of parasitic worm muscles, leading paralysis. in countries still permit use of levamisole, recommended dose anthelmintic therapy single dose, repeated dose 7 days later if needed severe hookworm infection. current commercial preparations intended veterinary use dewormer in cattle, pigs, , sheep. however, levamisole has gained prominence among aquarists effective treatment camallanus roundworm infestations in freshwater tropical fish.

cancer

after being pulled market in u.s. , canada in 1999 , 2003, respectively, levamisole has been tested in combination fluorouracil treat colon cancer. evidence clinical trials support addition fluorouracil therapy benefit patients colon cancer. in of leukemic cell line studies, both levamisole , tetramisole showed similar effect.

other

levamisole has been used treat variety of dermatologic conditions, including skin infections, leprosy, warts, lichen planus, , aphthous ulcers.

an interesting adverse side effect these reviewers reported in passing neurologic excitement . later papers, janssen group , others, indicate levamisole , enantiomer, dexamisole, have mood-elevating or antidepressant properties, although never marketed use of drug.